ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,427,347, issued on Sept. 30, was assigned to BioAtla Inc. (San Diego).

"Conditionally active anti-EpCAM antibodies, antibody fragments, their immunoconjugates and uses thereof" was invented by Jay M. Short (Jackson, Wyo.), Gerhard Frey (San Diego) and Hwai Wen Chang (San Marcos, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Isolated polypeptides having a heavy chain variable region and/or light chain variable region that specifically binds to EpCAM protein as well as antibodies and antibody fragments containing the heavy chain variable region and/or the light chain variable region that bind to EpCAM protein. Pharmaceutical compositions and kits...