ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,365, issued on March 25, was assigned to BETA PHARMA INC. (Wilmington, Del.).
"Organophosphorus-substituted compounds as c-MET inhibitors and therapeutic uses thereof" was invented by Don Zhang (Princeton, N.J.), Jirong Peng (Mequon, Wis.), Michael Nicholas Greco (Lansdale, Pa.), Michael John Costanzo (Warminster, Pa.) and Michael Alan Green (Easton, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides [1,2,4]triazolo[4,3-b][1,2,4]triazine, [1,2,4] triazolo[4,3-b]pyridazine, and [1,2,3]triazolo[4,5-b]pyrazine derivatives, and pharmaceutically acceptable salts, solvates or prodrugs thereof, as tyrosine kinase c-MET inhi...