US Patent Issued to Bayer, Bayer Pharma Aktiengsellschaft on Oct. 21 for "Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carbox-amide by racemate separation by means of diastereomeric tartaric acid esters" (German Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,381, issued on Oct. 21, was assigned to Bayer AG (Leverkusen, Germany) and Bayer Pharma Aktiengsellschaft (Berlin).

"Method for the preparation of (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1-6-naphthyridine-3-carbox-amide by racemate separation by means of diastereomeric tartaric acid esters" was invented by Johannes Platzek (Berlin), Kai Lovis (Dusseldorf, Germany) and Winfried Joentgen (Cologne, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a novel and improved process for preparing (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide o...