US Patent Issued to Bayer, Bayer Pharma, The Broad Institute, President and Fellows of Harvard College, The General Hospital on Dec. 2 for "2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH" (German, American, Chinese Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,248, issued on Dec. 2, was assigned to Bayer AG (Leverkusen, Germany), Bayer Pharma AG (Berlin), The Broad Institute Inc. (Cambridge, Mass.), President and Fellows of Harvard College (Cambridge, Mass.) and The General Hospital Corp. (Boston).

"2,4,5-trisubstituted 1,2,4-triazolones useful as inhibitors of DHODH" was invented by Stefan Nikolaus Gradl (Berlin), Duy Nguyen (Berlin), Knut Eis (Berlin), Judith Gunther (Berlin), Timo Stellfeld (Berlin), Andreas Janzer (Berlin), Sven Christian (Berlin), Thomas Muller (Langenfeld, Germany), Sherif EL Sheikh (Mulheim/Ruhr, Germany), Han Jie Zhou (Foster City, Calif.), Changjia Zhao (Beijing), David B. Sykes (Cambridge, Mass.), Steven James ...