US Patent Issued to BATTERJEE MEDICAL COLLEGE on Feb. 18 for "Disulfiram derivatives as ALDH1a1 and MAGL inhibitors" (Saudi Arabia Inventors)

ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,469, issued on Feb. 18, was assigned to BATTERJEE MEDICAL COLLEGE (Jeddah, Saudi Arabia).

"Disulfiram derivatives as ALDH1a1 and MAGL inhibitors" was invented by Ziad Omran (Jeddah, Saudi Arabia) and Omeima Abdullah (Makkah, Saudi Arabia).

According to the abstract* released by the U.S. Patent & Trademark Office: "A disulfiram derivative of formula (I)wherein R1 and R2 are independently -CH2CH2COOH, -CH2CH2COOEt, optionally substituted methylenepyridyl, optionally substituted methylenefuranyl, or optionally substituted methylenethiopenyl, may be useful in aldehyde dehydrogenase 1a1 (ALDH1a1) and/or monoacylglycerol lipase (MAGL)-mediated diseases or disorders. Such derivatives ma...