US Patent Issued to AVILAR THERAPEUTICS on May 6 for "ASGPR-binding compounds for the degradation of extracellular proteins" (Connecticut, Massachusetts Inventors)

ALEXANDRIA, Va., June 10 -- United States Patent no. 12,290,568, issued on May 6, was assigned to AVILAR THERAPEUTICS INC. (Waltham, Mass.).

"ASGPR-binding compounds for the degradation of extracellular proteins" was invented by Mark George Saulnier (Higganum, Conn.), Jesse Jingyang Chen (Lexington, Mass.), Srinivasa Karra (Pembrooke, Mass.), Kevin Tyler Sprott (Needham, Mass.), Jason Allan Wiles (Madison, Conn.) and Soumya Ray (Quincy, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds and compositions that have an asialoglycoprotein receptor (ASGPR) binding ligand bound to an extracellular protein binding ligand for the selective degradation of the target extracellular protein in vivo to treat ...