US Patent Issued to Avilar Therapeutics on May 27 for "Potent ASGPR-binding compounds for the degradation of immunoglobulins and other proteins" (Connecticut, Massachusetts Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,340, issued on May 27, was assigned to Avilar Therapeutics Inc. (Waltham, Mass.).

"Potent ASGPR-binding compounds for the degradation of immunoglobulins and other proteins" was invented by Jason Allan Wiles (Madison, Conn.), Srinivasa Karra (Pembrooke, Mass.), Mark George Saulnier (Higganum, Conn.), Jesse Jingyang Chen (Lexington, Mass.), Kevin Tyler Sprott (Needham, Mass.) and Soumya Ray (Quincy, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Extracellular protein degraders and compositions are provided that have a potent asialoglycoprotein receptor (ASGPR) Binding Ligand bound to an Extracellular Protein Targeting Ligand for the selective de...