US Patent Issued to Auckland Uniservices on Dec. 30 for "Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy" (New Zealander Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,268, issued on Dec. 30, was assigned to Auckland Uniservices Ltd. (Auckland, New Zealand).

"Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy" was invented by Brian Desmond Palmer (West Harbour, New Zealand), Lai Ming Ching (West Harbour, New Zealand) and Swarnalatha Akuratiya Gamage (Greenlane, New Zealand).

According to the abstract* released by the U.S. Patent & Trademark Office: "Pharmaceutical compositions comprising 3-aminoisoxazolopyridine compounds of the Formula I having IDO1 and/or TDO inhibitory activity are described, where W is CR1, N or N-oxide; X is CR2, N or N-oxide; Y is CR3, N or N-oxide; Z is CR4, N or N-oxide; and at least one of W,...