ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,570, issued on Oct. 14, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Ariz.).
"Conjugation of MCR1 ligand with cytotoxic drugs for treating skin cancer" was invented by Minying Cai (Tucson, Ariz.), Victor J. Hruby (Tucson, Ariz.) and Yang Zhou (Tucson, Ariz.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Ligand-drug conjugates for targeted melanoma therapies are disclosed herein. A ligand is conjugated to a cytotoxic cancer drug through a cleavage linker. The ligand can bind to an overexpressed receptor on a cancer cell, resulting in selectivity. This allows the drug to enter a cancer cell selectively and r...