US Patent Issued to ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA on Aug. 12 for "Disulfide-masked pro-chelator compositions and methods of use" (Arizona Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,518, issued on Aug. 12, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Ariz.).

"Disulfide-masked pro-chelator compositions and methods of use" was invented by Elisa Tomat (Tucson, Ariz.) and Eman A. Akam (Tucson, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Pro-chelator compositions featuring disulfide masks that upon activation yield active chelators. The pro-chelator compositions may be activated intracellularly, for example within cells featuring metal ion dysregulation, cells that proliferate abnormally, etc. The pro-chelators of the present invention include thiosemicarbazones, semicarbazones, a...