ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,067, issued on Aug. 5, was assigned to ARENA PHARMACEUTICALS INC. (San Diego).

"Methods of treating PAH with combinations of ralinepag and other agents" was invented by Dominic P. Behan (San Diego), John W. Adams (San Diego) and Lucie H. Clapp (London).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure encompasses combinations of ralinepag with a cGMP-elevating agent or prostanoid such as riociguat, treprostinil, or iloprost for treating PAH. The disclosed combination therapy provides for advantages such as improved efficacy, improved safety, reduced doses and/or frequency of ralinepag and/or riociguat, reduced doses and/or frequenc...