ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,244, issued on Aug. 5, was assigned to Antabio SAS (Labege, France).
"Diazabicyclooctanones as inhibitors of serine Beta-lactamases" was invented by Simon Leiris (Labege, France) and David Thomas Davies (Lebege, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a compound which is a diazabicyclooctanone of Formula (I) or a pharmaceutically acceptable salt thereof:wherein R is as defined herein. The compounds are useful in the treatment of bacterial infection, in particular they are useful in reducing bacterial resistance to antibiotics. They are also useful in the treatment of bacteria which express serine-Beta-lactamase ...