ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,226,456, issued on Feb. 18, was assigned to Amphastar Pharmaceuticals Inc. (Rancho Cucamonga, Calif.).

"Nasal powder formulation for treatment of hypoglycemia" was invented by Sankaram Mantripragada (Windsor, Colo.), Claude A. Piche (Verdun, Canada) and Jo Jan Filip Van Betsbrugge (Laval, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a powder formulation containing glucagon or a glucagon analog for nasal administration, useful in the treatment of hypoglycemia, and in particular the treatment of severe hypoglycemia. The present invention also provides a method of making this powder formulation, and to devices and me...