ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,681, issued on Oct. 14, was assigned to Amgen Inc. (Thousand Oaks, Calif.) and F.I.S.-FABBRICA ITALIANA SINTETICI SPA (Vicenza, Italy).
"Synthesis of sulfonamide intermediates" was invented by Neil Fred Langille (Sudbury, Mass.), Jason S. Tedrow (Salem, Mass.), Jonathan Vinh-Phu Truong (Thousand Oaks, Calif.), Robert Ronald Milburn (Belmont, Calif.) and Alessandro Arena (Vicenza, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are processes for synthesizing Mcl-1 inhibitors and intermediates such as compound Z that can be used to prepare them. In particular, provided herein are processes for synthesizing compound A1, and salts o...