US Patent Issued to Altor Bioscience, The USA, as represented by the Secretary, Dept. of Health and Human Services on June 10 for "Human immunodeficiency virus-specific T cell receptors" (Florida, Maryland, District Of Columbia Inventors)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,734, issued on June 10, was assigned to Altor Bioscience LLC (Culver City, Calif.) and The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Md.).

"Human immunodeficiency virus-specific T cell receptors" was invented by Peter Rhode (Miami), Mark Connors (Bethesda, Md.) and Stephen Migueles (Washington).

According to the abstract* released by the U.S. Patent & Trademark Office: "Engineered TCR molecules specific to retroviral peptide/HLA complexes guide direct killing and/or enable robust immune responses against HIV infected cells. In a first aspect, a TCR fusion polypeptide comprises a TCR variable alpha (VAlpha) domain, a TCR variable beta doma...