US Patent Issued to Alliance for Sustainable Energy, Vanderbilt University on Oct. 21 for "Guanidine degradation enzyme and methods of use" (Colorado, Tennessee Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,632, issued on Oct. 21, was assigned to Alliance for Sustainable Energy LLC (Golden, Colo.) and Vanderbilt University (Nashville, Tenn.).

"Guanidine degradation enzyme and methods of use" was invented by Jianping Yu (Golden, Colo.) and Bo Wang (Nashville, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Presented herein are Synechococcus strains engineered to express the bacterial ethylene-forming enzyme (EFE) that exhibit unstable ethylene production due to toxicity and genomic instability induced by accumulation of the EFE-byproduct guanidine. Co-expression of EFE and Sll1077 significantly enhanced genomic stability and enabled the resulting S...