US Patent Issued to Akouos on April 15 for "AAV-mediated delivery of therapeutic antibodies to the inner ear" (Massachusetts Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,960, issued on April 15, was assigned to Akouos Inc. (Boston).

"AAV-mediated delivery of therapeutic antibodies to the inner ear" was invented by Emmanuel John Simons (Brookline, Mass.), Robert Ng (Newton, Mass.) and Michael McKenna (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods that include introducing into an inner ear of a mammal a therapeutically effective amount of an adeno-associated virus (AAV) vector that includes a nucleotide sequence encoding (a) a polypeptide including an antibody heavy chain variable domain operably linked to a signal peptide and a polypeptide including an antibody light chain variable ...