ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,264, issued on June 17, was assigned to Akagera Medicines Inc. (Boxford, Mass.).
"Lipid nanoparticles for delivery of nucleic acids and methods of use thereof" was invented by Daryl C. Drummond (Lincoln, Mass.), Dmitri B. Kirpotin (San Francisco), Mark E. Hayes (Mill Valley, Calif.), Alexander Koshkaryev (Norwood, Mass.) and Ross B. Fulton (Southborough, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides for improved compositions of ionizable lipid nanoparticles for the delivery of therapeutic nucleic acids to cells. Cationic ionizable lipids are engineered with improved stability to oxidative degradation while in s...