ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,502,391, issued on Dec. 23, was assigned to AIVIVA BIOPHARMA INC. (Las Vegas).
"Multi-kinase inhibitors of VEGF and TGF beta and uses thereof" was invented by Gerald Woodrow DeVries (San Clemente, Calif.) and Diane Tang-Liu (Las Vegas).
According to the abstract* released by the U.S. Patent & Trademark Office: "A pharmaceutical composition for prevention or treatment of a disease or disorder characterized by chronic inflammation, associated with angiogenesis and fibrosis. The pharmaceutical composition includes a multi-target inhibitor, multi-phase modulator, or multi-kinase inhibitor, such as axitinib, nintedanib, pirfenidone, riociguat, sorafenib, sunitinib, lenvatinib, regorafenib...