US Patent Issued to Agency for Science, Technology and Research on Oct. 28 for "Method of increasing protein yield in mammalian cells in serum-free culture medium" (Singaporean Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,675, issued on Oct. 28, was assigned to Agency for Science, Technology and Research (Singapore).

"Method of increasing protein yield in mammalian cells in serum-free culture medium" was invented by Say Kong Ng (Singapore), Sow Zong Dawn Leong (Singapore), Gek Ling Janice Tan (Singapore) and Kah Hui Brian Teo (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method of growing and/or culturing mammalian cells, such as CHO or HEK293, in a serum-free cell culture medium that contains maltose as the sole carbohydrate source, or contains maltose and at least one other saccharide. In a preferred embodiment, the addi...