US Patent Issued to Agency for Science, Technology and Research, National University of Singapore on Sept. 30 for "Generation of midbrain-specific organoids from human pluripotent stem cells" (Singaporean Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,623, issued on Sept. 30, was assigned to Agency for Science, Technology and Research (Singapore) and National University of Singapore (Singapore).

"Generation of midbrain-specific organoids from human pluripotent stem cells" was invented by Junghyun Jo (Singapore), Huck Hui Ng (Singapore) and Hyunsoo Shawn Je (Singapore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a method of deriving and maintaining a midbrain-like organoid in culture, comprising (a) culturing pluripotent stem cells to obtain neuronal lineage embryoid bodies; (b) culturing the neuronal lineage embryoid bodies from (a) to obtain midbrain regionaliz...