ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,709, issued on March 18, was assigned to Accellta Ltd. (Haifa, Israel).
"Culture media for culturing pluripotent stem cells in suspension" was invented by Michal Amit (Misgav, Israel) and Itzchak Angel (Nes Ziona, Israel).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are defined culture media for culturing pluripotent stem cells in a suspension culture devoid of substrate adherence, the defined culture media comprising an effective amount of a protease inhibitor; a GSK3Beta inhibitor and at least one agent selected from the group consisting of a protease inhibitor and a WNT3A polypeptide; a WNT3A polypeptide and a stabilizing agent thereof...