US Patent Issued on Feb. 3 for "Lobinaline N-oxides as positive allosteric modulators of the dopamine transporter with potential value in the treatment of substance abuse disorders" (Kentucky Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,539,298, issued on Feb. 3.

"Lobinaline N-oxides as positive allosteric modulators of the dopamine transporter with potential value in the treatment of substance abuse disorders" was invented by John M. Littleton (Lexington, Ky.), Bert Lynn (Lexington, Ky.), Dennis T. Rogers (Lexington, Ky.) and Greg Gerhardt (Lexington, Ky.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The presently-disclosed subject matter describes Lobinaline N-oxides as modulators of the dopamine transporter. The presently-disclosed subject matter further describes to Lobinaline N-oxides as modulators of the nicotinic acetylcholine receptors. Also described herein are methods for tre...