Clinical Trial: To Determine the Effect of CYP Induction Following Administration of Nirogacestat in Healthy Adult Male Participants

U.S., Dec. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07259330) titled 'To Determine the Effect of CYP Induction Following Administration of Nirogacestat in Healthy Adult Male Participants' on Nov. 19.

Brief Summary: This study will evaluate the effects of nirogacestat 100 mg twice daily (BID) on the pharmacokinetics (PK) of a cytochrome P450 (CYP) cocktail.

Study Start Date: Nov. 17

Study Type: INTERVENTIONAL

Condition: Healthy

Intervention: DRUG: Nirogacestat

100 mg tablet Day 1 through Day 17

DRUG: Nirogacestat and Cocktail of CYP Specific Probe Substrates

Drug: Nirogacestat 100 mg tablet Day 1 through Day 17 and Drug: Cocktail of CYP Specific Probe Substrates administered Day 15.

Recruitmen...