U.S., Feb. 22 -- ClinicalTrials.gov registry received information related to the study (NCT06839352) titled 'Efficacy and Safety of Intravenous Vitamin K1 in Management of Acute Variceal Bleeding' on Jan. 27.
Brief Summary: The administration of Vitamin K1 (Vit-K1) injection is frequently utilized in clinical practice for managing upper gastrointestinal bleeding (UGIB) associated with liver cirrhosis, despite insufficient evidence supporting its effectiveness. This research aimed to assess the safety and efficacy of intravenous Vit-K1 in the management of acute variceal bleeding in cirrhotic patients.
This randomized, open-label clinical trial involved 66 cirrhotic cases with UGIB of suspected variceal origin. The cases were randomly assi...