U.S., July 15 -- ClinicalTrials.gov registry received information related to the study (NCT07062120) titled 'Efficacy and Safety of 30% Salicylic Acid and 10% Nicotinamide Combined Therapy in Melasma' on June 29.
Brief Summary: This prospective, randomized, placebo-controlled study evaluated the synergistic effects of 30% salicylic acid (SA) chemical peels and topical 10% nicotinamide (NAM) in 56 patients with moderate-to-severe melasma. Participants were divided into four groups: placebo control, SA peels alone (every 2 weeks for 8 sessions), NAM cream alone (twice daily for 16 weeks), and combination therapy (SA+NAM). The investigators investigated the efficacy and safety of 30%SA chemical peeling combined with 10% NAM.
Study Start Date...