Clinical Trial: A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo(R), in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT06948448) titled 'A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo(R), in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer' on April 21.

Brief Summary: The purpose of this study is to evaluate the safety and efficacy of two dose levels of ONO-4578 with Opdivo(R) when added to mFOLFOX6 and bevacizumab versus SOC as first-line treatment for advanced CRC.

Study Start Date: July 31, 2025

Study Type: INTERVENTIONAL

Condition: Colorectal Cancer

Intervention: DRUG: ONO-4578

ONO-4578 tablets once a day

DRUG: Opdivo(R)...