International Clinical Trial: An Open-label, Phase 2 Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

Geneva, Aug. 29 -- International Clinical Trials Registry received information related to the study (JPRN-jRCT2031250269) titled 'An Open-label, Phase 2 Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)' on Aug. 1.

Study Type: Interventional

Study Design: single arm study, open(masking not used), uncontrolled control, single assignment, treatment purpose

Primary Sponsor: Leedom H Nicole

Condition: Desmoid Tumor/Aggressive Fibromatosis

Intervention: IMP(Investigational Medicinal Product): Nirogacestat Nirogacestat 150 mg by mouth, twice daily

Recruitment Status: Not Recruiting

Phase: 2

Date of First Enrollment: 12/08/2025

Target Sample Size: 18

To know more, visit https://jrct.mhl...