U.S., July 30 -- ClinicalTrials.gov registry received information related to the study (NCT07092410) titled 'Surgical or Radiotherapeutic Intervention Concerning Large Singular Stable to Progressive Metastases in Patients With BRAFV600-mutated Melanoma Receiving Treatment With Encorafenib + Binimetinib' on July 07.
Brief Summary: This is an open-label, prospective, single arm study conducted in Germany to investigate local treatment (i.e. surgery or radiotherapy or electrochemotherapy) of metastases showing no response to encorafenib (E) + binimetinib (B) combination therapy and continuation of EB therapy afterwards.
The purpose of this study is to determine PFS of individual patients treated with local intervention while continuing thera...