U.S., Oct. 28 -- ClinicalTrials.gov registry received information related to the study (NCT05096195) titled 'PRevEnting FracturEs in Renal Disease - 1' on Sept. 21.
Brief Summary: PREFERRED-1 is a pilot study for a large randomized, pragmatic, open-label, comparative-effectiveness trial. The pilot will enroll at least 60 patients across 6 different hemodialysis centres in Ontario, Canada. Patients on outpatient maintenance hemodialysis at high risk of fragility fracture will be randomized 1:1 to denosumab vs. no-denosumab (i.e. usual care).
Study Type: Interventional
Condition: * Kidney Diseases
* Dialysis; Complications
* Fragility Fracture
* Chronic Kidney Disease-Mineral and Bone Disorder
Intervention: * Drug: Denosumab 60 mg/ml [...