U.S., Nov. 25 -- ClinicalTrials.gov registry received information related to the study (NCT07245056) titled 'Fetal Fornix and Hippocampus in Pregnant Women With Early-Onset Preeclampsia' on Nov. 15.
Brief Summary: Since early-onset preeclampsia (EOPE) is commonly associated with inadequate placentation, placental insufficiency, chronic fetal hypoxia, oxidative stress, and heightened inflammation, these pathological processes may adversely affect hippocampal neuronal development and maturation of axonal pathways such as the fornix. These mechanisms support our hypothesis that fetal fornix and hippocampus dimensions may be reduced in pregnancies complicated by EOPE, forming the scientific basis of our study.
Previous research has suggested ...