Clinical Trial: Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis

U.S., Dec. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07263425) titled 'Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Trastuzumab in Breast Cancer With Leptomeningeal Metastasis' on Nov. 24.

Brief Summary: Evaluate the efficacy and safety of Intrathecal Administration of Thiotepa in Combination with Trastuzumab via the Ommaya Reservoir in Breast Cancer with Leptomeningeal Metastasis

Study Start Date: Oct. 27

Study Type: INTERVENTIONAL

Condition: Leptomeningeal Metastasis of HER2-positive Breast Cancer

Intervention: DRUG: Intrathecal Administration of Thiotepa in Combination with Trastuzumab via the Ommaya Reservoir

Intrathecal chemotherapy group Patients receive...