U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07375654) titled 'Combined Use of Cyclosporine and Metformin in Treatment of Psoriasis vs Cyclosporine Alone' on Jan. 07.
Brief Summary: This study is a comparative clinical study evaluating the efficacy of combined therapy using cyclosporine and metformin versus cyclosporine alone in the treatment of psoriasis. Psoriasis is a chronic inflammatory skin disease that often requires systemic therapy in moderate to severe cases. Cyclosporine is an effective immunosuppressive agent; however, its long-term use is limited by potential adverse effects.
Metformin, a commonly used antidiabetic drug, has shown anti-inflammatory and immunomodulatory properties,...