U.S., March 14 -- ClinicalTrials.gov registry received information related to the study (NCT06874205) titled 'Assessment of 11C-JMJ-129 for Imaging PDE4D in Brain and Whole Body of Healthy Volunteers' on March 12.
Brief Summary: Background:
PDE4D is a protein in the body that plays a role in thinking and depression. This protein may play a major role in disorders such as Alzheimer disease or major depressive disorder. To learn more about these disorders, researchers want to be able to detect levels of PDE4D in the brain. 11C-JMJ-129 is a new radiotracer (a radioactive substance that highlights parts of the body during imaging scans) that was developed to attach only to PDE4D.
Objective:
To test the new radiotracer 11C-JMJ-129 during ima...