Clinical Trial: A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

U.S., Dec. 18 -- ClinicalTrials.gov registry received information related to the study (NCT07290062) titled 'A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)' on Dec. 04.

Brief Summary: The primary objective of this dose-finding study is to evaluate the safety, tolerability and pharmacodynamics of single dose of INS1202 via IT administration in participants >= 18 to <80 years of age with ALS who carry superoxide dismutase type 1 (SOD1) mutations or harbor no known ALS-related genetic mutation.

Study Start Date: Dec. 31

Study Type: INTERVENTIONAL

Condition: Amyotrophic Lateral Sclerosis

Intervention: GENETIC: INS1202

Suspe...