Clinical Trial: A Study to Assess the Efficacy and Safety of PRT-042 Nasal Spray for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

U.S., Sept. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07193901) titled 'A Study to Assess the Efficacy and Safety of PRT-042 Nasal Spray for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide' on Sept. 01.

Brief Summary: The purpose of this study is to learn about:

* To evaluate the efficacy of PRT-042 nasal spray for the Rapid Reduction of the depressive symptoms in adults with major depressive disorder (MDD) with acute suicidal ideation or behavior

* To evaluate the safety and pharmacokinetic (PK) characteristics after multiple dose of PRT-042 nasal spray in adults with major depressive d...