Clinical Trial: A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial to Evaluate the Safety and Pharmacokinetic Profile of Single and Multiple Dose Escalation Topical Dermal Administration of SHR0302 Alkali Gel in Healthy Subjects

U.S., Aug. 2 -- ClinicalTrials.gov registry received information related to the study (NCT07098117) titled 'A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial to Evaluate the Safety and Pharmacokinetic Profile of Single and Multiple Dose Escalation Topical Dermal Administration of SHR0302 Alkali Gel in Healthy Subjects' on July 27.

Brief Summary: This study is divided into two parts, the first part is a single-dose dose escalation trial (SAD) in healthy subjects; The second part is a multiple-dose dose escalation trial (MAD) in healthy subjects.

Study Start Date: June 19, 2024

Study Type: INTERVENTIONAL

Condition: Preoperative Sedation of Adults

Intervention: DRUG: SHR0302 Base Gel

Part I: once daily. Part 2:, twi...