Clinical Trial: A Clinical Trial Testing the Safety of BNT327 (an Investigational Drug) and How Well it Works in Patients With Recurrent Glioblastoma

U.S., Dec. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07297212) titled 'A Clinical Trial Testing the Safety of BNT327 (an Investigational Drug) and How Well it Works in Patients With Recurrent Glioblastoma' on Dec. 09.

Brief Summary: This multi-site Phase II study will enroll adults with histologically confirmed diagnosis of World Health Organization (WHO) Grade IV glioblastoma (GBM) consistent with WHO central nervous system (CNS) 2021 criteria who have received prior first-line treatment including with at least radiotherapy and temozolomide, with a Karnofsky performance status (KPS) >=60, adequate organ function, and at least one measurable lesion according to the response assessment in neuro-oncology...