Singapore Clinical Trial: A Phase 2, Randomized, Open-Label Study of VVD-133214 in Combination with Pembrolizumab compared with Pembrolizumab monotherapy in participants with advanced colorectal adenocarcinoma (CRC) harboring microsatellite instability (MSI) and/or deficient mismatch repair (DMMR)

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'A Phase 2, Randomized, Open-Label Study of VVD-133214 in Combination with Pembrolizumab compared w... Read More

Clinical Trial: Correlation Between Artificial Intelligence-Based Fecal Coverage Area-Quantified Bowel Preparation Quality Score (FQ-BBPS) and Adenoma Detection Rate

U.S., Sept. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07795788) titled 'Correlation Between Artificial Intelligence-Based Fecal Coverage Area-Quantified Bowel Prep... Read More

Singapore Clinical Trial: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (modified FOLFIRINOX or Gemcitabine plus Nab-paclitaxel) with or without Zoldonrasib (RMC 9805) as First-line Treatment in Patients with Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma (RASolute 305)

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemothera... Read More

Singapore Clinical Trial: A longitudinal study to investigate innate immune reprogramming following Herpes Zoster vaccination and its impact on subsequent vaccination response

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'A longitudinal study to investigate innate immune reprogramming following Herpes Zoster vaccinatio... Read More

Singapore Clinical Trial: Phase I/II study of Mezigdomide and Elranatamab for relapsed/refractory multiple myeloma patients (MELT-MM)

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'Phase I/II study of Mezigdomide and Elranatamab for relapsed/refractory multiple myeloma patients ... Read More

Singapore Clinical Trial: Phase Ib/II Study of Tislelizumab in Combination with Bevacizumab and Capecitabine in Advanced Solid Tumors with Evaluation in Immunotherapy-Resistant and Central Nervous System Disease (TIBEC)

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'Phase Ib/II Study of Tislelizumab in Combination with Bevacizumab and Capecitabine in Advanced Sol... Read More

Singapore Clinical Trial: A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose Study to Evaluate the Gastric Emptying Delay, Pharmacokinetics, Safety, and Tolerability of Eloralintide in Participants with Obesity or Overweight

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose St... Read More

Singapore Clinical Trial: A Phase 1, Multicenter, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients with Advanced Solid Tumors

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Multicenter, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pha... Read More

Clinical Trial: Markers of Efficacy to Immunotherapy in Patients With Metastatic Melanoma

U.S., Sept. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07794501) titled 'Markers of Efficacy to Immunotherapy in Patients With Metastatic Melanoma' on Aug. 25. Bri... Read More

Singapore Clinical Trial: A Phase 1 randomized, double-blind, placebo-controlled, single-ascending-dose study investigating the safety and tolerability of ARD001 in healthy adult subjects and a Phase 2 open-label, multiple-dose study in adult subjects with hemophilia A

Singapore, Sept. 1 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 randomized, double-blind, placebo-controlled, single-ascending-dose study investigating ... Read More

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