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Singapore Clinical Trial: A phase II, multicenter, open-label, single arm study to evaluate the safety and efficacy of asciminib in pediatric participants newly diagnosed or previously treated with Philadelphia positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) with or without known T315I mutation.

Singapore, Oct. 1 -- The Health Sciences Authority received information related to the study titled 'A phase II, multicenter, open-label, single arm study to evaluate the safety and efficacy of ascimi... Read More


Singapore Clinical Trial: A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with chemotherapy followed by asciminib plus blinatumomab in pediatric, adolescent, and young adult participants with relapsed or refractory BCR::ABL1-positive (Philadelphia positive, Ph+) or BCR::ABL1-like (Ph-like) acute lymphoblastic leukemia (ALL)

Singapore, Oct. 1 -- The Health Sciences Authority received information related to the study titled 'A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with ... Read More


Singapore Clinical Trial: A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC determined ineligible for PD(L)1 therapy based on PD-L1 negative disease

Singapore, Oct. 1 -- The Health Sciences Authority received information related to the study titled 'A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy v... Read More


Singapore Clinical Trial: CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel and Gemcitabine versus Placebo in Combination with Nab-paclitaxel and Gemcitabine in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion

Singapore, Oct. 1 -- The Health Sciences Authority received information related to the study titled 'CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel... Read More


Clinical Trial: Improving ILD Screening in Patients With RA and SSc Using EHR-Embedded CDS and PRO Tools

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07849673) titled 'Improving ILD Screening in Patients With RA and SSc Using EHR-Embedded CDS and PRO Tools' on... Read More


Clinical Trial: Study of Single Doses of HBS-104 in Acutely Sleep-deprived Healthy Participants

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07848659) titled 'Study of Single Doses of HBS-104 in Acutely Sleep-deprived Healthy Participants' on Sept. 09... Read More


Clinical Trial: Effects of Video LMA Cuff Pressure in Tympanoplasty.

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07849322) titled 'Effects of Video LMA Cuff Pressure in Tympanoplasty.' on Sept. 24. Brief Summary: This pros... Read More


Clinical Trial: A Clinical Study of Alimatravir (MK-8527) in Transgender (Trans) and Gender Diverse Individuals on Gender-affirming Hormone Therapy and at Low Likelihood of Human Immunodeficiency Virus (HIV)-1 Exposure (MK-8527-018)

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07850609) titled 'A Clinical Study of Alimatravir (MK-8527) in Transgender (Trans) and Gender Diverse Individu... Read More


Clinical Trial: Real-World Lenvatinib Sequencing in Unresectable Hepatocellular Carcinoma (uHCC)

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07849660) titled 'Real-World Lenvatinib Sequencing in Unresectable Hepatocellular Carcinoma (uHCC)' on Sept. 2... Read More


Clinical Trial: Contrast-enhanced Ultrasound Evaluation of Indeterminate Ovarian Lesions: Prospective Multicenter Study

U.S., Oct. 1 -- ClinicalTrials.gov registry received information related to the study (NCT07849543) titled 'Contrast-enhanced Ultrasound Evaluation of Indeterminate Ovarian Lesions: Prospective Multic... Read More