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Singapore Clinical Trial: A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with chemotherapy followed by asciminib plus blinatumomab in pediatric, adolescent, and young adult participants with relapsed or refractory BCR::ABL1-positive (Philadelphia positive, Ph+) or BCR::ABL1-like (Ph-like) acute lymphoblastic leukemia (ALL)

Singapore, Aug. 23 -- The Health Sciences Authority received information related to the study titled 'A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with... Read More


Singapore Clinical Trial: A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC determined ineligible for PD(L)1 therapy based on PD-L1 negative disease

Singapore, Aug. 23 -- The Health Sciences Authority received information related to the study titled 'A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy ... Read More


Singapore Clinical Trial: CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel and Gemcitabine versus Placebo in Combination with Nab-paclitaxel and Gemcitabine in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion

Singapore, Aug. 23 -- The Health Sciences Authority received information related to the study titled 'CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxe... Read More


Singapore Clinical Trial: A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Plus Adjuvant Chemotherapy Versus Placebo Plus Adjuvant Chemotherapy in Stage IB-IIIA NSCLC Patients with Uncommon EGFR Mutations Following Complete Tumor Resection (REZILIENT4)

Singapore, Aug. 23 -- The Health Sciences Authority received information related to the study titled 'A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Plus Ad... Read More


Clinical Trial: VR for Steroid Joint Injections - Feasibility

U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07778069) titled 'VR for Steroid Joint Injections - Feasibility' on Aug. 17. Brief Summary: The goal of the ... Read More


Clinical Trial: Lidocaine-prilocaine Cream as Analgesia for In-office Levator Muscle Trigger Point Injections

U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07778043) titled 'Lidocaine-prilocaine Cream as Analgesia for In-office Levator Muscle Trigger Point Injectio... Read More


Clinical Trial: Effect of a Femoral Venting Hole on Embolic Load in Prophylactic Intramedullary Nailing

U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07778238) titled 'Effect of a Femoral Venting Hole on Embolic Load in Prophylactic Intramedullary Nailing' on... Read More


Clinical Trial: Cardiovascular Impact of the Menstrual Cycle and Contraception - Longitudinal Evaluation

U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07779447) titled 'Cardiovascular Impact of the Menstrual Cycle and Contraception - Longitudinal Evaluation' o... Read More


Clinical Trial: CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity

U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07778771) titled 'CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survi... Read More


Clinical Trial: TRTME: Improving Outpatient Initiation of Medication for Opioid Use Disorder Following Hospitalization

U.S., Aug. 22 -- ClinicalTrials.gov registry received information related to the study (NCT07780097) titled 'TRTME: Improving Outpatient Initiation of Medication for Opioid Use Disorder Following Hosp... Read More