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Singapore Clinical Trial: A Phase 2/3 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination with Osimertinib as First-Line Treatment in Patients with Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Singapore, March 25 -- The Health Sciences Authority received information related to the study titled 'A Phase 2/3 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab ... Read More


Singapore Clinical Trial: A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Retained Gastric Contents Using Gastric Ultrasound in Participants with Type 2 Diabetes Mellitus and Participants with Overweight or Obesity without Type 2 Diabetes Mellitus.

Singapore, March 25 -- The Health Sciences Authority received information related to the study titled 'A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Re... Read More


Singapore Clinical Trial: A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy in Participants With 1L Locally Advanced Unresectable/Metastatic Esophageal Cancer: KEYMAKER-U06 Substudy 06E

Singapore, March 25 -- The Health Sciences Authority received information related to the study titled 'A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination W... Read More


Singapore Clinical Trial: EASi-PROTKT™ - A Phase III double-blind, randomised, parallel-group superiority trial to evaluate efficacy and safety of the combined use of oral vicadrostat (BI 690517) and empagliflozin compared with placebo and empagliflozin in participants with type 2 diabetes, hypertension and established cardiovascular disease

Singapore, March 25 -- The Health Sciences Authority received information related to the study titled 'EASi-PROTKT™ - A Phase III double-blind, randomised, parallel-group superiority trial to evaluate... Read More


Clinical Trial: Dynamic Effect of Occlusal Vertical Dimension on Lower Facial Form and Lip Positions

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07491640) titled 'Dynamic Effect of Occlusal Vertical Dimension on Lower Facial Form and Lip Positions' on M... Read More


Clinical Trial: Medication Withdrawal in Stable HF With Improved LVEF

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07489547) titled 'Medication Withdrawal in Stable HF With Improved LVEF' on March 18. Brief Summary: The go... Read More


Clinical Trial: Becotatug Vedotin Combined With Cetuximab in the Later-line Treatment of Metastatic RAS Wild-type Colorectal Cancer

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07490119) titled 'Becotatug Vedotin Combined With Cetuximab in the Later-line Treatment of Metastatic RAS Wi... Read More


Clinical Trial: GS1-144 in Participants With Hepatic Impairment and Healthy Female

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07491289) titled 'GS1-144 in Participants With Hepatic Impairment and Healthy Female' on March 18. Brief Su... Read More


Clinical Trial: Variation in Viscoelastic Properties of Pulmonary Mucus in Patients Undergoing Mechanical Ventilation

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07490028) titled 'Variation in Viscoelastic Properties of Pulmonary Mucus in Patients Undergoing Mechanical ... Read More


Clinical Trial: Trans-Oral Sampling as an Alternative Surveillance of Barrett's Esophagus Pilot

U.S., March 25 -- ClinicalTrials.gov registry received information related to the study (NCT07490340) titled 'Trans-Oral Sampling as an Alternative Surveillance of Barrett's Esophagus Pilot' on Oct. 1... Read More