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Singapore Clinical Trial: A Phase 1, Randomized, Placebo-Controlled, Single Ascending Dose-Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4167586 in Participants with Obesity or Overweight who are Otherwise Healthy.

Singapore, Aug. 3 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Randomized, Placebo-Controlled, Single Ascending Dose-Escalation Study to Investigate th... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)

Singapore, Aug. 3 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy o... Read More


Singapore Clinical Trial: A Phase III, 52-week, prospective, randomized, double-blind, placebo-controlled, parallel-group, multi-center study, with a primary efficacy endpoint at 12 weeks, to determine the efficacy, safety, and tolerability of fixed doses of 15 mg bid and 30 mg bid of evenamide as add-on in patients with documented treatment-resistant schizophrenia, which is not adequately controlled by a stable therapeutic dose of the patient’s current antipsychotic medication(s).

Singapore, Aug. 3 -- The Health Sciences Authority received information related to the study titled 'A Phase III, 52-week, prospective, randomized, double-blind, placebo-controlled, parallel-group, mu... Read More


Singapore Clinical Trial: A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer

Singapore, Aug. 3 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab ... Read More


Clinical Trial: Effect of Intraoperative Amino Acid Administration on Postoperative Renal Function in Patients Undergoing Open Abdominal Aortic Aneurysm Repair: A Single-Center Retrospective Cohort Study (Japan)

Tokyo, Aug. 3 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062442) titled 'A Retrospective Observational Study of the Association Between Intraoperativ... Read More


Clinical Trial: Evaluation of the clinical utility of a novel EUS-FNB needle for solid pancreatic lesions: a multicenter prospective observational study (Japan)

Tokyo, Aug. 3 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062435) titled 'An observational study of endoscopic ultrasound-guided tissue sampling for s... Read More


Clinical Trial: A phase II study of sotorasib plus panitumumab rechallenge in patients with KRAS G12C mutant metastatic colorectal cancer (Japan)

Tokyo, Aug. 3 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062434) titled 'A phase II study of sotorasib plus panitumumab rechallenge in patients with ... Read More


Clinical Trial: Clinical Utility of the Aerobika Oscillating Positive Expiratory Pressure Device for Airway Secretion Clearance in Patients with Asthma and Allergic Bronchopulmonary Mycosis (ABPM): A Prospective Observational Study (Japan)

Tokyo, Aug. 3 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062433) titled 'Clinical Utility of the Aerobika Oscillating Positive Expiratory Pressure De... Read More


Clinical Trial: Evaluation of the Effects of a Test Food on Lipid-Related Parameters --A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Comparative Trial-- (Japan)

Tokyo, Aug. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062420) titled 'Evaluation of the Effects of a Test Food on Lipid-Related Parameters --A Ran... Read More


Clinical Trial: Evaluation of the Body Fat-Reducing Effect of Continuous Consumption of the Test Food in Conjunction with Dietary Improvement (Japan)

Tokyo, Aug. 2 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000062414) titled 'Evaluation of the Body Fat-Reducing Effect of Continuous Consumption of the ... Read More