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Singapore Clinical Trial: Role of glucagon-like peptide 1 receptor Agonist (GLP1 RA) Dulaglutide on cerebral hemodynamics In patients with severe and symptomAtic steNosis of inTracranial internal carotid artery or middle cerebral artery with impaired cerebral vasodilatory reserve- an open-label randomised clinical trial (RADIANT)

Singapore, April 19 -- The Health Sciences Authority received information related to the study titled 'Role of glucagon-like peptide 1 receptor Agonist (GLP1 RA) Dulaglutide on cerebral hemodynamics I... Read More


Singapore Clinical Trial: A randomized, placebo-controlled, participant- and investigator-blinded study to evaluate the efficacy in reducing atrial fibrillation burden (AFB) as well as the safety, tolerability, and pharmacokinetics of oral PKN605 in participants with atrial fibrillation

Singapore, April 19 -- The Health Sciences Authority received information related to the study titled 'A randomized, placebo-controlled, participant- and investigator-blinded study to evaluate the eff... Read More


Singapore Clinical Trial: A Phase 2/3 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab Adizutecan in Combination with Osimertinib as First-Line Treatment in Patients with Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

Singapore, April 19 -- The Health Sciences Authority received information related to the study titled 'A Phase 2/3 Randomized Study to Evaluate the Safety, Efficacy, and Optimal Dose of Telisotuzumab ... Read More


Singapore Clinical Trial: A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Retained Gastric Contents Using Gastric Ultrasound in Participants with Type 2 Diabetes Mellitus and Participants with Overweight or Obesity without Type 2 Diabetes Mellitus.

Singapore, April 19 -- The Health Sciences Authority received information related to the study titled 'A Study to Evaluate the Effect of Fasting Duration and Temporary Withholding of Tirzepatide on Re... Read More


Singapore Clinical Trial: A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination With Pembrolizumab (MK-3475) With or Without Chemotherapy in Participants With 1L Locally Advanced Unresectable/Metastatic Esophageal Cancer: KEYMAKER-U06 Substudy 06E

Singapore, April 19 -- The Health Sciences Authority received information related to the study titled 'A Phase 1/2 Open-Label, Umbrella Platform Design Study of Investigational Agents in Combination W... Read More


Clinical Trial: A prospective randomized controlled trial comparing absorbable (VICRYL USP 2) and non-absorbable (ETHIBOND USP 2) sutures for deep layer closure in cervical laminoplasty: evaluation of postoperative neck pain, nuchal ligament continuity, and imaging outcomes (Japan)

Tokyo, April 19 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061284) titled 'A prospective randomized trial comparing absorbable and non-absorbable sut... Read More


Clinical Trial: Rethinking B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in hemodialysis patients (Japan)

Tokyo, April 20 -- UMIN Clinical Trials Registry (UMIN-CTR) received information related to the study (UMIN000061311) titled 'Rethinking B-type natriuretic peptide and N-terminal pro-B-type natriureti... Read More


Clinical Trial: Coenzyme Q10 as Adjunctive Therapy in Drug-Resistant Epilepsy

U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07537283) titled 'Coenzyme Q10 as Adjunctive Therapy in Drug-Resistant Epilepsy' on April 06. Brief Summary... Read More


Clinical Trial: Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically Castrated Prostate Cancer Patients

U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07535905) titled 'Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically C... Read More


Clinical Trial: Effect of DFM on Quadriceps Spasticity in Stroke Patients

U.S., April 18 -- ClinicalTrials.gov registry received information related to the study (NCT07537322) titled 'Effect of DFM on Quadriceps Spasticity in Stroke Patients' on April 02. Brief Summary: Th... Read More