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Clinical Trial: Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCD

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07773246) titled 'Phase 1/2 Study of KRRO-121 in Healthy Volunteers and Patients With UCD' on Aug. 14. Brief... Read More


Singapore Clinical Trial: An open-label study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of BAY 3771249 as monotherapy or combination with other cancer treatments in participants with solid tumors harboring a KRAS G12D mutation

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'An open-label study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and ... Read More


Clinical Trial: Study of Zanzalintinib in Children and Adolescents With Relapsed or Refractory Solid Tumors

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07773454) titled 'Study of Zanzalintinib in Children and Adolescents With Relapsed or Refractory Solid Tumors... Read More


Singapore Clinical Trial: A phase II, multicenter, open-label, single arm study to evaluate the safety and efficacy of asciminib in pediatric participants newly diagnosed or previously treated with Philadelphia positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) with or without known T315I mutation.

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A phase II, multicenter, open-label, single arm study to evaluate the safety and efficacy of ascim... Read More


Singapore Clinical Trial: A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with chemotherapy followed by asciminib plus blinatumomab in pediatric, adolescent, and young adult participants with relapsed or refractory BCR::ABL1-positive (Philadelphia positive, Ph+) or BCR::ABL1-like (Ph-like) acute lymphoblastic leukemia (ALL)

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with... Read More


Singapore Clinical Trial: A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC determined ineligible for PD(L)1 therapy based on PD-L1 negative disease

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy ... Read More


Clinical Trial: Progressive Muscle Relaxation and Deep Breathing Exercises in Patients With COPD

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07773194) titled 'Progressive Muscle Relaxation and Deep Breathing Exercises in Patients With COPD' on Aug. 1... Read More


Singapore Clinical Trial: CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel and Gemcitabine versus Placebo in Combination with Nab-paclitaxel and Gemcitabine in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxe... Read More


Clinical Trial: New Functional Ingredient for Oral Care

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07771907) titled 'New Functional Ingredient for Oral Care' on June 22. Brief Summary: The goal of this clini... Read More


Clinical Trial: LineMatrix(R) Biological Vascular Graft for the Creation of Arteriovenous Graft

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07773051) titled 'LineMatrix(R) Biological Vascular Graft for the Creation of Arteriovenous Graft' on Aug. 12... Read More