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Singapore Clinical Trial: An Open-Label Study to Investigate the Long-Term Effects of Acoramidis on Cardiac Function, Structure and Cardiac Amyloid Burden in Participants with Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'An Open-Label Study to Investigate the Long-Term Effects of Acoramidis on Cardiac Function, Structu... Read More


Singapore Clinical Trial: A Phase 1, Open-Label, Randomized, Crossover Study to Investigate the Relative Bioavailability of Abemaciclib (LY2835219) Test and Reference Formulations and an Alternate Administration Method, in Healthy Participants

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Open-Label, Randomized, Crossover Study to Investigate the Relative Bioavailability of A... Read More


Singapore Clinical Trial: Solid tumor Study for Long term Treatment of Cancer Patients Who Have Participated in BMS-Parent Studies Investigating Adagrasib (BMS-986503)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'Solid tumor Study for Long term Treatment of Cancer Patients Who Have Participated in BMS-Parent St... Read More


Singapore Clinical Trial: A Global, Multicentre, Phase II Platform Study of Datopotamab Deruxtecan (Dato-DXd)-based Combinations in Adult Participants With TROP2 NMR-positive Non-small Cell Lung Cancer (NSCLC) (PATAGONIA)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'A Global, Multicentre, Phase II Platform Study of Datopotamab Deruxtecan (Dato-DXd)-based Combinati... Read More


Singapore Clinical Trial: A Phase Ib, Open-Label, Multicenter Study of EBC-129 Combined With Osimertinib in Patients With Advanced EGFR-Mutated, Osimertinib-Resistant Non–Small Cell Lung Cancer (NSCLC)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase Ib, Open-Label, Multicenter Study of EBC-129 Combined With Osimertinib in Patients With Adv... Read More


Singapore Clinical Trial: ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants with Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Comp... Read More


Singapore Clinical Trial: A Phase 2, Randomized, Open-Label Study of VVD-133214 in Combination with Pembrolizumab compared with Pembrolizumab monotherapy in participants with advanced colorectal adenocarcinoma (CRC) harboring microsatellite instability (MSI) and/or deficient mismatch repair (DMMR)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 2, Randomized, Open-Label Study of VVD-133214 in Combination with Pembrolizumab compared wi... Read More


Singapore Clinical Trial: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (modified FOLFIRINOX or Gemcitabine plus Nab-paclitaxel) with or without Zoldonrasib (RMC 9805) as First-line Treatment in Patients with Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma (RASolute 305)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherap... Read More


Singapore Clinical Trial: A longitudinal study to investigate innate immune reprogramming following Herpes Zoster vaccination and its impact on subsequent vaccination response

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'A longitudinal study to investigate innate immune reprogramming following Herpes Zoster vaccination... Read More


Singapore Clinical Trial: Phase I/II study of Mezigdomide and Elranatamab for relapsed/refractory multiple myeloma patients (MELT-MM)

Singapore, Aug. 5 -- The Health Sciences Authority received information related to the study titled 'Phase I/II study of Mezigdomide and Elranatamab for relapsed/refractory multiple myeloma patients (... Read More